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Old 10-08-2011
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Biochemistry Directly affected by Citrate

The activity of which of the following enzymes is directly affected by citrate?
A. Fructose-2,6-bisphosphatase
B. Isocitrate dehydrogenase
C. Phosphofructokinase I
D. Pyruvate carboxylase
E. 6-phosphogluconate dehydrogenase
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Old 10-08-2011
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D.pyruvate decarboxylase

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Old 10-08-2011
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it is C: Phosphofructokinase 1
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Old 10-11-2011
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The only enzyme that is directly affected by citrate is C Phosphofructokinase 1 (PFK-1). Citrate inhibits the enzyme.
Pyruvate carboxylase is affacted by Acetyl-CoA and not by citrate.

Can anyone remind me what reaction does 6-phosphogluconate dehydrogenase catalyze?

Thanks!

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Old 10-11-2011
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Quote:
Originally Posted by Relid View Post
The only enzyme that is directly affected by citrate is C Phosphofructokinase 1 (PFK-1). Citrate inhibits the enzyme.
Pyruvate carboxylase is affacted by Acetyl-CoA and not by citrate.

Can anyone remind me what reaction does 6-phosphogluconate dehydrogenase catalyze?

Thanks!

It catalyses the conversion of 6-phosphogluconate into ribulose 5-p, generating 1 NADPH in the process (it's part of the Pentose Phosphate Pathway).

And i'm going with C
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