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Old 10-09-2011
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Question Raynoud's Phenomenon Q?

A 49 -year-old white female comes to your office complaining of painful, cold fingers tips, which turn white when she is hanging out her laundry. While there is no approved treatment for this condition at this time, which of the following drugs has been shown to be useful?

A) Propanolol (Inderal)
B) Nifedipine (Procardia)
C) Atenolol (Tenormin)
D) Methysergide (Sansert)
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B) Nifedipine
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Old 10-09-2011
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B. Nifedipine (vasodilate)
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B) Nifedipine (Procardia)
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Ca antagonist Nifedipine....she should also wear gloves avoiding stress and cold exposure..

Most cases that have only raynaud ....they dont have an autoimmune...but tests have to be done
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Nifedepinee !.

What class of drug is the last one?
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Correct Answer Answer

Answer: B is correct. Nifedipine is the calcium channel blocker of choice in patients with Raynaudís disease. Beta blockers can produce arterial insufficiency of the Raynaudís type, so propanolol and atenolol would be contraindicated. Drugs such as ergotamine preparations and methysergide can produce cold sensitivity, and should, therefore, be avoided in patients with Raynaudís disease.


To USMLE2011m:
Methysergide is a prescription drug used for prophylaxis of migraine headaches. Methysergide interacts with serotonin (5-HT) receptors. Antagonist of 5-HT2B/2C and 5-HT1A receptors.
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B) Nifedipine (Procardia)
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