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Old 03-10-2015
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Default simple partial seizure vs myoclonic seizure

how to differentiate simple partial seizure with motor feature vs. myoclonic seizure by clinical symptom?
I think they both have no loss of consciousness and have motor symptoms.
how to differentiate them on exam since the treatments are totally different.
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Old 03-10-2015
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Don't get too hung up on this. Its confusing and many ways to explain them, and different books tell you different things. Here is how the boards will test you:

Simple Partial Seizure: By definition, a simple partial seizure means the conscious is intact, and there are focal abnormal location that fire up from time to time. They happen in attacks, and the children are usually conscious at that time. They are called partial because entire one side of the body is paralyzed or rhythmically contracting.

Myoclonic seizures are different. They happen EARLY in the morning, and are precipitated by sleep deprivation and stress. The mother will bring her child, usually a boy, who complains that he has seizures of his legs as soon as he wakes up. He will also tell you that it precipitates with sleep deprivation or when he is in exams, some sort of stress. The board point is that they get treated specifically with Valproic Acid.

That's all you need to know for Step1. I could go into detail, but that is CK and Step3.

Hope that helps!
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And for USMLE simple partial treat with CBZ ?
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Thanks so much! @ Smashingdude.
partial seizures including simple and complex, treatment is CBZ
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Quote:
Originally Posted by shidox View Post
And for USMLE simple partial treat with CBZ ?
There are only guidelines, and proven anti-convulsants for a few type of seizures. Most others, you can't really pick between phenytoin, CBZ, valproate, Lamotrigine, Gabapentin, CCB's etc. The boards want to know the associations, and the side effects. So,

Absence seizures -> Treat with Ethusoximide
Myoclonic seizures -> Treat with Valproate

All others -> Can use any. No first line. Know the side effects.

Oh also, Tic Doulereux (Trigeminal Neuralgia) -> Treat with CBZ

Know the side effects, especially Phenytoin. Lamotrigine causes SJS syndrome. CBZ causes agranulocytosis. Valproate causes folate deficiencies, NTD's.
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