Duodenal ulcers versus gastric ulcers; relation to food? - USMLE Forums
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Old 10-13-2011
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GIT Duodenal ulcers versus gastric ulcers; relation to food?

Why duodenal ulcers are classically relieved by food, while gastric ulcers are exacerbated by it ?
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Old 10-13-2011
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For duodenal ulcers the reason for it because you have release of HCO3 by brunner glands when food enters that area. So people eat more because to relieves the pain because the bicarb release. That is why you see hypertrophy of the glands in these patients.

For gastric by eating you release more acid that increases the symptoms so people eat less and so they present as people with decreased weight and pain on eating.
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