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Old 03-11-2015
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Default Genetics Question..plz help!

Im having difficulty understanding the following question from Kaplan genetics chapter 2 review questions: (sry tried uploading the image but it isn't working)

8. A man who is a known carrier of oculocutaneous albinism marries his half cousin (they share a common grandparent). This trait is transmitted as a fully penetrant autosomal recessive. What is the probability that this couple will produce a child with this disorder?

A. 1/2
B. 1/4
C. 1/8
D. 1/16
E. 1/64

**how do v calculate the probability of wife being a heterozygote/homozygote when her parents and grandparents are shown phenotypically normal in the pedigree??
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Old 03-11-2015
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i will try without cheating.

Aa[aa+AA+Aa]=the cousin can have three probabilities AA,Aa,aa i will assume the cousin has no albism which is somehow implied in the question therefore i will reduce it to


a=recessive allele
A=dorminant allele
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