Elevated coagulation factors in Nephrotic Syndrome! - USMLE Forums
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Old 10-15-2011
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Kidney Elevated coagulation factors in Nephrotic Syndrome!

Why patients with nephrotic syndrome have elevated serum coagulation factors such as vWF, fibrinogen etc.? What is the mechanism?
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Old 10-15-2011
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Because you have low albumin in nephrotic syndrome, the liver will try to compensate by synthesizing more proteins.

The proteins produced by the liver include lipoproteins and clotting factors.

That's why you have hyperlipidemia and thrombosis in patients with nephrotic syndrome.
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The above post was thanked by:
HaipengWang (10-15-2011), jahn77 (10-15-2011), MANIAKOS (10-15-2011)


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