Cell Bio Practice Qs - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 03-17-2015
USMLE Forums Newbie
 
Steps History: Not yet
Posts: 2
Threads: 2
Thanked 1 Time in 1 Post
Reputation: 11
Default Cell Bio Practice Qs

1. cystic fibrosis occurs because of a mutation in the gene that codes for an active transport(CFTR) in lung tissue that is responsible for transporting chloride ions from the interior lung surface into the cell. In the mutated protein, chloride ions are not transported across cell membranes, and build up in the extracellular fluid. About 1 in 2000 humans inherit a mutation in the CFTR transporter and show symptoms of the disease

2. The CFTR transporter is a
a. Cl- glucose antiporter
b. Voltage gated anion pump
c. ATP activated Cl- pump
d. Cl- uniporter
e. E. Neurotransmitter gated Cl- channel

3. The cell death cascade becomes irreversible once
a. intiator procaspases become activated
b. executioner procaspases become activated
c. cells form blebs
d. the FAS ligand binds to G protein coupled receptors
e. when IAP proteins bind activated caspases

4. if cervical epithelium is subject to papilloma virus invasion genetic damage is likely to occur. The infected cells will continue to grow and divide despite being directed to die. Which perturbed protein activities would direct such a cell fate?
a. activation of pyruvate kinase
b. inactivation of tumor suppressor genes
c. activation of trnacription factors (TF) for interferon genes that induce P53 expression
d. over expression of FAS death receptor proteins
e. Mutagenic deletion of the pro-domain on executor caspases

5. The biochemical markers of programmed cell death include
a. cytotoxicity
b. DNA digestion by endonucleases
c. Formation of mitotic spindles
d. Massive exocytosis
e. Uptake of water by osmosis

6. After mitosis completes the formation of a pair of daughter nuclei, cytokinesis finishes the cell cycle by dividing the cell in two. Which is true of cytokinesis?
a. it occurs at the start of S-phase
b. it is activated by expression of c-cyclin (cytokinesis) and C-cyclin-dependent kinases (C-CDK)
c. tubulin rearrangements (assembly and dynesin mediated contraction) form the cleavage furrow
d. position of the contractile ring (comprised of actin and myosin proteins) is determined by signals emanating from the microtubules of the mitotic spindle (the inter-polar microtubules)
e. the two daughter cells potion themselves to enter s-phase

7. a patient with adnvanced stage ebola infection will be bleeding from their eyes, mouth, nose, and anus. This hemorrhaging is caused activating and exhausting the supply of all the seren proteases that are normally used to activate thrombin and fibirin during clot formation. By what mechanism are these proteases kept active in a healthy human

a. they are sequestered in microsomes
b. they are expressed as pro-proteins or zymogens
c. they are bound and transported by serum albumin
d. they are inhibited by alkaline pH
e. they are inactivated by glycosylation

8. which of the following is true
a. tumor initiators introduce mutations into the DNA of somatic cells
b. benign cancers invade surrounding tissues and colonize distant organs
c. benign tumors induce apoptosis in response to cell stress or DNA damage
d. metastatic cancers activate the intrinsic but not extrinsic apoptosis pathway
e. cancer cells acquire stable genetic phenotypes

Last edited by drgrad; 03-17-2015 at 10:14 PM.
Reply With Quote Quick reply to this message
The above post was thanked by:
moriamo (08-12-2015)



  #2  
Old 08-12-2015
USMLE Forums Newbie
 
Steps History: Not yet
Posts: 1
Threads: 0
Thanked 0 Times in 0 Posts
Reputation: 10
Default

please where did you get these questions from?
Reply With Quote Quick reply to this message
  #3  
Old 08-12-2015
USMLE Forums Scout
 
Steps History: Not yet
Posts: 97
Threads: 28
Thanked 27 Times in 19 Posts
Reputation: 37
Default

Quote:
Originally Posted by drgrad View Post
1. cystic fibrosis occurs because of a mutation in the gene that codes for an active transport(CFTR) in lung tissue that is responsible for transporting chloride ions from the interior lung surface into the cell. In the mutated protein, chloride ions are not transported across cell membranes, and build up in the extracellular fluid. About 1 in 2000 humans inherit a mutation in the CFTR transporter and show symptoms of the disease

2. The CFTR transporter is a
a. Cl- glucose antiporter
b. Voltage gated anion pump
c. ATP activated Cl- pump
d. Cl- uniporter
e. E. Neurotransmitter gated Cl- channel

3. The cell death cascade becomes irreversible once
a. intiator procaspases become activated
b. executioner procaspases become activated
c. cells form blebs
d. the FAS ligand binds to G protein coupled receptors
e. when IAP proteins bind activated caspases

4. if cervical epithelium is subject to papilloma virus invasion genetic damage is likely to occur. The infected cells will continue to grow and divide despite being directed to die. Which perturbed protein activities would direct such a cell fate?
a. activation of pyruvate kinase
b. inactivation of tumor suppressor genes
c. activation of trnacription factors (TF) for interferon genes that induce P53 expression
d. over expression of FAS death receptor proteins
e. Mutagenic deletion of the pro-domain on executor caspases

5. The biochemical markers of programmed cell death include
a. cytotoxicity
b. DNA digestion by endonucleases
c. Formation of mitotic spindles
d. Massive exocytosis
e. Uptake of water by osmosis

6. After mitosis completes the formation of a pair of daughter nuclei, cytokinesis finishes the cell cycle by dividing the cell in two. Which is true of cytokinesis?
a. it occurs at the start of S-phase
b. it is activated by expression of c-cyclin (cytokinesis) and C-cyclin-dependent kinases (C-CDK)
c. tubulin rearrangements (assembly and dynesin mediated contraction) form the cleavage furrow
d. position of the contractile ring (comprised of actin and myosin proteins) is determined by signals emanating from the microtubules of the mitotic spindle (the inter-polar microtubules)
e. the two daughter cells potion themselves to enter s-phase

7. a patient with adnvanced stage ebola infection will be bleeding from their eyes, mouth, nose, and anus. This hemorrhaging is caused activating and exhausting the supply of all the seren proteases that are normally used to activate thrombin and fibirin during clot formation. By what mechanism are these proteases kept active in a healthy human

a. they are sequestered in microsomes
b. they are expressed as pro-proteins or zymogens
c. they are bound and transported by serum albumin
d. they are inhibited by alkaline pH
e. they are inactivated by glycosylation

8. which of the following is true
a. tumor initiators introduce mutations into the DNA of somatic cells
b. benign cancers invade surrounding tissues and colonize distant organs
c. benign tumors induce apoptosis in response to cell stress or DNA damage
d. metastatic cancers activate the intrinsic but not extrinsic apoptosis pathway
e. cancer cells acquire stable genetic phenotypes
2. E?
3. A?
4. E?
5. D?
6. D?
7. B
8. A


This was super hard. Am I the only one who thinks so? I suck at this.
Reply With Quote Quick reply to this message



Reply

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
molecular and cell bio samusmle33 USMLE Step 1 Forum 1 03-12-2015 08:17 AM
bio rehaf alagha USMLE Step 1 Forum 1 03-03-2014 08:25 AM
Cell micro bio HY source sky_blue2000 USMLE Step 1 Forum 0 08-25-2013 02:34 PM
cell bio pathophysio1 USMLE Step 1 Forum 1 09-19-2012 09:39 PM
Bio chem Q drgsarunprasath USMLE Step 1 Forum 9 08-15-2011 02:50 AM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)