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  #1  
Old 10-17-2011
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Question Lung Pathology in ALL child Q?

A four-year old girl who had acute lymphoblastic leukemia in remission with immunosuppressive chemotherapy, referred to the hospital because of progressive tachycardia and dyspnea since 3 days ago. In spite of initial admission work up and resuscitation she died. Lung necropsy demonstrated that alveolar spaces were lined by multi-nucleated giant cells with intranuclear and intracytoplasmic eosinophilic inclusion bodies.


What is the most likely cause of this condition?

A) Cytomegalovirus
B) Mycoplasma Tuberculosis
C) Mycoplasma pneumonia
D) Pneumocystis jiroveci
E) Klebsiella
F) Measles
G) Coxiella burnetti
H) Herpes simplex
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  #2  
Old 10-17-2011
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I will choose F) Measles. Because it typically forms multi-nucleated giant cells with intranuclear and intracytoplasmic eosinophilic inclusion bodies.

Not Cytomegalovirus. Although CMV is big with intra-nuclear inclusion bodies, it is NOT multi-nucleated.
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Old 10-18-2011
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Its giant celk pneumonia caused by complication of measles or varicella zoster
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  #4  
Old 10-18-2011
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Correct Answer Answer

Measles is the answer
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