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Old 10-21-2011
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Bacteria Bowed tibias, deafness, and flattened nose!

A 9 yr old girl is brought to the physician because of outward bowing of her anterior tibias, deafness, and a flattened nose. With which of the following drugs should this patient have been treated to prevent this condition?

[A] Acyclovir
[B] Ciprofloxacin
[C] Ganciclovir
[D] Isoniazid and rifampin
[E] Penicillin
[F] Sulfadiazine

Source: Kaplan Step 1 Qbank
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Old 10-21-2011
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Penicillin
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Old 10-21-2011
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Congenital syphilis - penicillin
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Old 10-21-2011
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The correct answer is E. This question is essentially asking the reader to diagnose the condition in the mother that would lead to the development of the signs and symptoms in the child. Then the reader must determine what the treatment of choice is for the mother's infectious condition. TORCH is an acronym referring to a group of microorganisms that lead to specific pathologic changes that occur during fetal or neonatal infection. The T stands for toxoplasma, the O for others, the R for rubella, the C for cytomegalovirus, and the H for herpes simplex virus. The "others" portion of TORCH include syphilis and tuberculosis as well as a few other less common microorganisms.
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The above post was thanked by:
Cairo (10-21-2011), drhnis (10-22-2011), medkary (11-08-2011)



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