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Old 03-31-2015
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Default SCID

FA mentions that findings for SCID includes decreased T-cell receptor excision circle (TREC)

I don't understand what TREC is?
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Old 03-31-2015
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God bless Wikipedia :

T-cell receptor excision circles (TRECs) are small circles of DNA created in T-cells during their passage through the thymus as they rearrange their TCR genes.[1] Their presence indicates maturation of T cells; TRECs are reduced in SCID (Severe combined immunodeficiency disease).
Single joint T-cell receptor excision circles (sjTRECs) were in the news as a way to test the age of the individual from a blood sample.[2] The detection of sjTRECs can be further used as a diagnostic tool to monitor the thymic output e.g. following hematopoietic stem cell transplantation or in case of AIDS [3]
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