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  #1  
Old 10-23-2011
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Neuro JC Virus Target CNS Cells!

Which of the following cells in the CNS is the primary target for JC virus?

A) Oligodendrocytes and Astrocytes
B) Oligodendrocytes and Microglia
C) Astrocytes and Microglia
D) Primary Cortical Neurons and Cerebellar Purkinje Cells
E) Oligodendrocytes and Cerebellar Purkinje Cells
F) Astrocytes and Cerebellar Purkinje Cells

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Old 10-23-2011
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a) Oligo and astro is most abundant cells, probably JC attacks them (degeneration is everywhere)
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Old 10-23-2011
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i go for A but i am not sure i want to know the answer and any explanation available
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Old 10-23-2011
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Correct Answer Answer

Quote:
Originally Posted by dr.muhamad View Post
i go for A but i am not sure i want to know the answer and any explanation available
JCV can cross the blood-brain barrier into the central nervous system, where it infects oligodendrocytes and astrocytes. In the brain it causes the usually fatal progressive multifocal leukoencephalopathy, or PML, by destroying oligodendrocytes.
JC virus causes progressive multifocal leukoencephalopathy in immunodeficient patients.
It is also associated with leukemia or lymphoma.
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Old 10-24-2011
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C for sure!!
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Old 10-24-2011
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c for sure!!
wrong!!!!!
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Old 10-24-2011
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It is oligodendrocytes and astrocytes
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Old 10-25-2011
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A) Oligodendrocytes and Astrocytes
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Microbiology-, Nervous-System-, Pathology-, Step-1-Questions

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