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  #1  
Old 10-25-2011
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Blood Azurophilic, needle-shaped intracellular material

A 47-year-old male presents with 2 weeks of recurrent fevers and fatigue. A peripheral blood smear is shown; the pathologist’s report indicates occasional presence of azurophilic, needle-shaped intracellular material. What is the likely diagnosis?

A. Hodgkin’s lymphoma
B. Acute Promyelocytic Leukemia
C. Multiple myeloma
D. Chronic lymphocytic leukemia
E. Hairy cell leukemia

Azurophilic, needle-shaped intracellular material-blood-film-image.jpg
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  #2  
Old 10-25-2011
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It is auer rod in aml m3
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  #3  
Old 10-25-2011
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dont know it...i m with b cause i think the other options dont seem right
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  #4  
Old 10-25-2011
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B. Acute Promyelocytic Leukemia
dx by exclusion
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  #5  
Old 10-25-2011
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I also go with B.
Is the figure representing a peripheral blood smear or bone marrow?
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  #6  
Old 10-25-2011
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i think its D coz in image there are no auer rods ... and look at age its 47 years old so 40 to 60 CLL common so i think its D
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  #7  
Old 10-25-2011
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Correct Answer

B is the answer. The description supports B than other options
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  #8  
Old 10-26-2011
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Looks like B, but where are the Auer rods?? ...and the age (47) does not go with APML
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Old 10-26-2011
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i think B. Acute Promyelocytic Leukemia Auer rods azurophilic, needle-shaped intracellular inclusions!
D. CLL may be,but unlike smuge cell
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Old 10-27-2011
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yup it is b
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