Originally Posted by yagoy
Can someone please explain why TIBC increases in pregnancy and OCP use while % transferring saturation decreases?
thanks in advance.
Your body needs more iron in pregnancy to make more hemoglobin etc and some ppl develop iron deficiency anemia, ( it can also happen if ur pre pregnancy iron stores were at the lower scale of normal)
like all causes of iron def anemia, ferritin goes down, TIBC increases (low ferritin causes transferrin to increase) because there are more sites
on transferrin to bind iron so its capacity is increased
in low iron states. And % sat of transferrin decreases because transferrin is not saturated
with enough iron .