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Old 11-09-2011
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Question Renal Pathology

The 10-year-old daughter of a United Nations ambassador in Turkey develops a severe sore throat, which resolves after a few days. Ten days later, the mother notices dark stains on the child's underwear and takes her to the pediatrician. A urine sample appears smoky, and red cell casts are noted in the urinary sediment. If a renal biopsy were obtained from this child it would probably show
A. dense deposits
B. fusion of podocyte foot processes
C. linear deposition of IgG
D. mesangial IgA deposits
E. subepithelial humps
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Old 11-09-2011
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A. dense deposits

which appear as a "lumpy bumpy" areas.....
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Old 11-09-2011
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Subepithelial himps
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Old 11-09-2011
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Quote:
Originally Posted by belindalimm View Post
The 10-year-old daughter of a United Nations ambassador in Turkey develops a severe sore throat, which resolves after a few days. Ten days later, the mother notices dark stains on the child's underwear and takes her to the pediatrician. A urine sample appears smoky, and red cell casts are noted in the urinary sediment. If a renal biopsy were obtained from this child it would probably show
A. dense deposits
B. fusion of podocyte foot processes
C. linear deposition of IgG
D. mesangial IgA deposits
E. subepithelial humps
i guess it is E
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Old 11-09-2011
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e . . . . . .
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Old 11-09-2011
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the presence of subepithelial humps is the hallmark for diagnostics in biopsy for acute post steptococcal glomerulonephritis although IgG deposits can be too present
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Old 11-09-2011
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Quote:
Originally Posted by scopusmount View Post
the presence of subepithelial humps is the hallmark for diagnostics in biopsy for acute post steptococcal glomerulonephritis although IgG deposits can be too present
Yes, it's the subepithelial humps(E). But how do you know it had steptococcal infection first although the child was undergoing a sore throat before?
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