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Old 11-09-2011
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Default which kind of hepatitis?

i have this question and i dont know its answer,,,hope to know your opinions
A man with jaundice and the live biopsy shows portal fibrosis with lymphatic infiltrates ,,and THE BILIARY TRACTS INSIDE THE LIVER ARE DISTENDED ,,so he is asking which of the following antibodies will we find??
1-anti-smith
2-anti-mitochondrial
3-anti-smooth muscle

please if anyone knows the answer,i would like to hear the explanation
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Old 11-09-2011
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Primary Biliary Cirrhosis--anti-mitochondrial ab
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Old 11-09-2011
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Quote:
Originally Posted by USMLE234 View Post
Primary Biliary Cirrhosis--anti-mitochondrial ab
i like this answer
but then i saw it is a man not a woman and what about the distended biliary tracts inside the liver(idk what does that should mean to me)
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Old 11-09-2011
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Autoimmune dx are more common in women. Having said that, it's not uncommon for men to have them too. And, all of the answer choices are pointing towards an autoimmune condition, so the gender of the patient shouldn't matter at that point, see what Im saying?

Also, given the history and the findings, it suggests PBC. PBC is characterized by destruction of intrahepatic bile ducts with eventual liver failure.

Anti-SM ab is associated with autoimmune hepatitis

Anti-smith is associated with SLE.
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Old 11-09-2011
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Quote:
Originally Posted by USMLE234 View Post
Autoimmune dx are more common in women. Having said that, it's not uncommon for men to have them too. And, all of the answer choices are pointing towards an autoimmune condition, so the gender of the patient shouldn't matter at that point, see what Im saying?

Also, given the history and the findings, it suggests PBC. PBC is characterized by destruction of intrahepatic bile ducts with eventual liver failure.

Anti-SM ab is associated with autoimmune hepatitis

Anti-smith is associated with SLE.
thank you
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