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Old 11-13-2011
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Heart Aortic Stenosis & increased Contratility with preload

Was wondering if anyone knew the reason behind why preload is not changed with aortic stenosis and decreased with increased contractility.

Aortic Stenosis - if time is systole is cut short then why is preload only minimal changed? Wouldn't the blood that was not ejected out (that should have if a normal heart) still be there to add to the blood that will enter during filling?

Increased Contractility - If stroke volume increases then shouldn't the amount returning to the heart increase (Since venous return (VR) = preload = EDV & Cardiac output (CO) )? If you look at cardiac function curve, the CO line move up and to left so increase CO or VR.
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Old 11-13-2011
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its really confusing but what i think that with mild or moderate aortic stenosis the preload is not changed due to compunsatory mechanism of the heart that hypertrophy to pump more blood so that end systolic volume still keep it within the normal range
while with increased contractility u are decreasing the end systolic volume and theory u are decreasing the end diastolic volume > so decreasing the preload
,, i tried to figure this really confusing statment as possible
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