Q. klinefelter syndrome - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 05-20-2015
USMLE Forums Addict
 
Steps History: ---
Posts: 137
Threads: 62
Thanked 3 Times in 3 Posts
Reputation: 13
Default Q. klinefelter syndrome

In klinefelter syndrome, there is dysgenesis of seminiferous tubules and as a result - both inhibin secretion from sertoli cells and testosterone production from leyding sells decreases. But, How estrogen and estrogen/testosterone ratio increases in klinefelter syn., can anybody pls explain this.Thanks.
Reply With Quote Quick reply to this message



  #2  
Old 05-20-2015
Hassan8's Avatar
USMLE Forums Addict
 
Steps History: Step 1 Only
Posts: 141
Threads: 26
Thanked 50 Times in 32 Posts
Reputation: 60
Default

The decreased testosterone in klinefelters leads to decreased feedback inhibition and thus increased LH from the pitutary. This LH actually causes increased aromatase in fat tissue which converts the adrenal androgens into estrogen.

Last edited by Hassan8; 05-20-2015 at 03:08 AM.
Reply With Quote Quick reply to this message
  #3  
Old 05-20-2015
USMLE Forums Addict
 
Steps History: ---
Posts: 137
Threads: 62
Thanked 3 Times in 3 Posts
Reputation: 13
Default

thanks hassan. But, can u pls confirm is it LH or FSH that stimulate aromatase production by adipose tissue? I am asking this because as I was discussing with my friend, he was mentioning that increase in FSH stimulates aromatase production.So, just wanted to make sure of it.
Reply With Quote Quick reply to this message
  #4  
Old 12-23-2015
USMLE Forums Scout
 
Steps History: ---
Posts: 20
Threads: 9
Thanked 0 Times in 0 Posts
Reputation: 10
Default please help

In klinefelter, if there is an anemia, what the cause of that problem? is it bacause of androgen deficiency? so the erythropoiesis be suppressed

need your explanation
Reply With Quote Quick reply to this message



Reply

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
androgen insensitvity syndrome vs testicular regression syndrome swwal USMLE Step 2 CK Forum 6 10-25-2015 09:45 PM
Plz Help Superconfused with Klinefelter's Syndrome wa87el USMLE Step 1 Forum 2 08-24-2014 04:29 PM
Klinefelter Syndrome Doctor Ali USMLE Step 1 Bits & Pieces 0 01-14-2013 02:02 PM
Man In Barrel Syndrome versus Locked In Syndrome Androide89 USMLE Step 1 Forum 7 12-04-2010 11:47 PM
Differentiating Staphylococcal Scalded Skin Syndrome from Toxic Epidermal Necrolysis and Steven Johnson Syndrome lee-usmle USMLE Step 2 CK Bits & Pieces 0 03-21-2010 07:12 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)