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Old 11-29-2011
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Help Fast fibers vs slow fibers; NBME concept

Please help me with this concept...
I understand the role of fast and slow fibers but here slow fiber is doing weight training..what would be the effect? would it be changed into fast fiber ?
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well even i was stuck on this question for quiet a while and it's a very important topic. my friend recently got a similar question on her exam
here's what i think .. the # of mitochondria does NOT increase..( because that's what differentiates slow and fast fibers in the first place!
increase in Actin filaments is kind of useless unless there's increase of Mysoin. so that doesn't change too
finally, first i thought that yes the muscle fibers Increase in number, but then muscles undergo HYPERTOPHY! and not hyperplasia.. so that means this variable doesn't change either!!

somebody correct me if I'm wrong
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Its D the number of mitochondria increases by weightlifting but the amount of actin myosin remains same just remember it in this way that muscles are a bit tense in bodybuilders and as u know that muscles are permanent cells so it cannot divide so its D i hope its clear and easy now! ( but one imp thing we can see muscke regeneration after injury but that not due to myocytes proliferation thats due to pericyte surrounding the myocytes they proliferate )
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Quote:
Originally Posted by yasirsattar75 View Post
Its D the number of mitochondria increases by weightlifting but the amount of actin myosin remains same just remember it in this way that muscles are a bit tense in bodybuilders and as u know that muscles are permanent cells so it cannot divide so its D i hope its clear and easy now! ( but one imp thing we can see muscke regeneration after injury but that not due to myocytes proliferation thats due to pericyte surrounding the myocytes they proliferate )
oh yes i jus googles , u r right. mitochondrai do increase!!
thanx!!
wens ur exam?
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but isnt Quadriceps type 1 fiber? if someone do weightbearing exercise to type 1 fiber ..how can mitochondrias increase?
it seems stupid but isnt that weight bearing exercise increases type 2 fibers which have few mitochondrias?
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Quote:
Originally Posted by shyangel18 View Post
oh yes i jus googles , u r right. mitochondrai do increase!!
thanx!!
wens ur exam?
My exam is after 4 hours m just revising some stuff right now n making myself feeling relax its 4:38am here will go to promectric at 8:30
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Goodluck!!
do enlighten us with ur experience!!
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Default different answer

got this from online, pls forgive the length:

Satellite Cells
Satellite cells function to facilitate growth, maintenance and repair of damaged skeletal (not cardiac) muscle tissue (2). These cells are termed satellite cells because they are located on the outer surface of the muscle fiber, in between the sarcolemma and basal lamina (uppermost layer of the basement membrane) of the muscle fiber. Satellite cells have one nucleus, with constitutes most of the cell volume.
Usually these cells are dormant, but they become activated when the muscle fiber receives any form of trauma, damage or injury, such as from resistance training overload. The satellite cells then proliferate or multiply, and the daughter cells are drawn to the damaged muscle site. They then fuse to the existing muscle fiber, donating their nuclei to the fiber, which helps to regenerate the muscle fiber. It is important to emphasize the point that this process is not creating more skeletal muscle fibers (in humans), but increasing the size and number of contractile proteins (actin and myosin) within the muscle fiber (see Table 1. for a summary of changes that occur to muscle fibers as they hypertrophy). This satellite cell activation and proliferation period lasts up to 48 hours after the trauma or shock from the resistance training session stimulus (2).

The amount of satellite cells present within in a muscle depends on the type of muscle. Type I or slow-twitch oxidative fibers, tend to have a five to six times greater satellite cell content than Type II (fast-twitch fibers), due to an increased blood and capillary supply (2). This may be due to the fact that Type 1 muscle fibers are used with greatest frequency, and thus, more satellite cells may be required for ongoing minor injuries to muscle.


from this you can see that the numberand size of actin do increase.
this is just my take on this i am not very sure
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