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Old 12-05-2011
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Immunology Complement Deficiency and Penile Discharge

An 18-year-old male states that he has pus coming out of his penis. He has also been experiencing fevers, chills and nausea. He admits to having intercourse with a prostitute several weeks ago. A gram stain of the penile discharge is shown in the figure. Which of the following deficiencies puts him at risk for this disease?
  • A. C1 only
  • B. C5 - C9
  • C. C3 only
  • D. C1 - C3
  • E. C2 only
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Old 12-05-2011
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b. C5 - c9
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Old 12-05-2011
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neisseria

B
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Old 12-05-2011
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B. C5 - C9

because C5-C9 form the MAC which is crucial to lyse the cell....
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Old 12-05-2011
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B. C5-9 required for formation of membrane attack complex!!
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Old 12-05-2011
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C5-9 deficiency associated with Neisseria gonorrhoea infections- Those gram negative diplococcus inside the PMN'S
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Old 12-06-2011
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Quote:
Originally Posted by daulath singh View Post
C5-9 deficiency associated with Neisseria gonorrhoea infections- Those gram negative diplococcus inside the PMN'S
yup exactly its C5-C9
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Old 12-06-2011
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Star For further info quick and easy manner

CLICK ON THIS LINK http://emedicine.medscape.com/articl...yes::rolleyes:

FOR INFO REGARDING PATHOPHYSIOLOGY OF NEISSERIA GONORRHEA CLICK http://emedicine.medscape.com/articl...overview#a0104

Last edited by CHAKRAM; 12-06-2011 at 07:36 AM.
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Old 12-06-2011
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Not only gonorrhea, C5-C9 def is associated with Neisseria infections, gonorrhea and meningitides.
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