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#1
12-05-2011
 USMLE Forums Veteran Steps History: Not yet Posts: 281 Threads: 74 Thanked 131 Times in 68 Posts Reputation: 141
Third generation in the pedigree

Given this pedigree,

Click image to enlarge

What would be expected of the III generation?

a) The probable pattern of inheritance shown by the disease in this family is autosomal recessive.
b) If recombination does not occur the probability that III 1 will be affected if she has an AB marker genotype is 1.
c) If recombination does not occur, the probability that III 1 will be affected if she has a BB marker genotype is 1.
d) If the recombination fraction between the disease and marker loci equals 0.04, the probability that III 1 will be affected if she inherits an AB marker genotype equals 0.96.
 The above post was thanked by: riya10 (12-07-2011)

#2
12-05-2011
 USMLE Forums Veteran Steps History: Not yet Posts: 281 Threads: 74 Thanked 131 Times in 68 Posts Reputation: 141

reposted from another member nevertheless mindboggling
#3
12-05-2011
 USMLE Forums Veteran Steps History: Step 1 Only Posts: 277 Threads: 36 Thanked 158 Times in 95 Posts Reputation: 168

no idea, this pedigree stuff just drives me nutS!
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#4
12-05-2011
 USMLE Forums Guru Steps History: 1 + CS Posts: 300 Threads: 22 Thanked 97 Times in 62 Posts Reputation: 107

ccccccccccccccc
#5
12-05-2011
 USMLE Forums Veteran Steps History: Not yet Posts: 281 Threads: 74 Thanked 131 Times in 68 Posts Reputation: 141

Quote:
Could you pls post the explanation
#6
12-05-2011
 USMLE Forums Master Steps History: 1+CK+CS+3 Posts: 653 Threads: 47 Thanked 408 Times in 249 Posts Reputation: 418

hey people, i'm having a hard time with the pedigree q's, any recommendations?

 Tags Genetics-

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