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#1




Calculating the carrier frequency in a population!
Cystic fibrosis is an autosomal recessive disease, if the incidence of disease in white population is 1/2500, then which of the following is appropriate carrier frequency of this Mendelian trait in this population ???????
a) 1/12 b) 1/25 c) 1/50 d) 1/125 e) 1/625 Please reply with explanation? 
The above post was thanked by:  
doxorubicin (12072011), riya10 (12072011) 
#2




1/25 as q squared is 1/2500 so q will be 1/50 and 2pq assuming p=1 is 1/25.
Am i correct 
#3




Quote:
thanx 


#6




In Q,we have to find the heterozygote prevalence 2pq.
It is the prevalence of disease. 
#7




Quote:
1/25 
#8




no,no no,, actually i asked 1/2500 is incidence or prevalence of disease . . ?

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BiostatisticsEpidemiology, Genetics, Step1Questions 
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