GFR in nephrectomy - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 12-05-2011
USMLE Forums Veteran
 
Steps History: Not yet
Posts: 281
Threads: 74
Thanked 132 Times in 69 Posts
Reputation: 142
Kidney

In nephrectomy the GFR falls only by 25% as the other kidney manages to compensate ie increases it filtration fraction. Could some one please explain what compensatory mechanisms help in the other kidney to filter at higher pressure

Maybe its because of increased surface area of nephrons. Am I correct?
Reply With Quote Quick reply to this message



  #2  
Old 12-05-2011
USMLE Forums Scout
 
Steps History: 1+CK+CS
Posts: 53
Threads: 2
Thanked 20 Times in 17 Posts
Reputation: 30
Default

Quote:
Originally Posted by indigo View Post
In nephrectomy the GFR falls only by 25% as the other kidney manages to compensate ie increases it filtration fraction. Could some one please explain what compensatory mechanisms help in the other kidney to filter at higher pressure

Maybe its because of increased surface area of nephrons. Am I correct?
As kidneys are arranged in parallel, removing one kidney increases the resistance of whole system. this increases the pressure.
Reply With Quote Quick reply to this message
  #3  
Old 12-06-2011
USMLE Forums Veteran
 
Steps History: Not yet
Posts: 281
Threads: 74
Thanked 132 Times in 69 Posts
Reputation: 142
Default

Quote:
Originally Posted by rise View Post
As kidneys are arranged in parallel, removing one kidney increases the resistance of whole system. this increases the pressure.
Increasing the pressure will lead to afferent vasoconstriction and efferent vasodilation as the renin angiotensin system inhibited. So the increase in pressure will not cause an increase in FF in the normal kidney. But there is an element of hypertrophy and hyperplasia in the normal kidney but I cannot understand what promotes it
Reply With Quote Quick reply to this message



Reply

Tags
Physiology-, Renal-

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)