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Old 12-06-2011
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Biochemistry substrate level phosphorylation and oxidative phosphorylation

can somebody explain substrate level phosphorylation and oxidative phosphorylation?
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Old 12-06-2011
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Substrate level phosphorylation:

In it,substrate phosphate used by kinases to make ATP, for example 1,3 bisphosphoglycerate converted to 3 phosphoglycerate by phosphoglycerate kinase enzyme to make ATP (in this process,oxygen not used ).

Oxidative phosphorylation:

Pyruvate formed by glycolysis in cytoplasm goes to mitochondria metablized,finally electrons handed over to ETC ,in 2nd last step of ETC, oxygen is utilized to make water (oxygen and H+ =water ) and in last step,protons utilized to make ATP.

Watch this as well.


http://www.1lec.com/Biochemistry/Ele...ain/index.html
(posted by Evelina Todd )

Hope it will clear your concept.
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Old 12-06-2011
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Simply.. Oxidative uses oxygen and ETC. While substrate level uses INORGANIC PHOSPHATE (Pi) directly to make ATP. wIthout using NADH n stuff
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