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  #1  
Old 12-09-2011
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Question Failure to pass meconium syndrome!

Male infant fails to pass meconium in first 24 hrs. Examination shows dimple in place of anal opening in perineum. What other additional defects likely found?

A. tracheo-esophageal fistula
B. vertebral anomalies
C. urogenital defects
D. cardiac abnormalities
E. ileal atresia

Please explain your answer
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Old 12-09-2011
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UROGENITAL DEFECTS

Because if fistula present, meconium may discharge from vagina or urethra.
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Old 12-09-2011
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ur rt its urogenital...

i was jus thnkg tat VACTERL defects are mesodermal abnorm
however anal canal whetr it abov petinate will b endodermal or below will be ectodermal in origin
so how is it part of VACTERL defcts??
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Old 12-09-2011
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I am not convinced about this answer, where does it say in Kaplan?
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Old 12-09-2011
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Its imperforated anus so it presents with urogenital abnormalities its uw question i thinkso lol ! atresia is above the pectineal line that presents with VACTERL defects and anal canal below pectinate line is ectodermal origion and above mesodermal origion !
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Old 12-09-2011
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Imperforate anus is associated with an increased incidence of some other specific anomalies as well, together being called the VACTERL association:
  • V - Vertebral anomalies
  • A - Anal atresia
  • C - Cardiovascular anomalies
  • T - Tracheoesophageal fistula
  • E - Esophageal atresia
  • R - Renal (Kidney) and/or radial anomalies
  • L - Limb defects
Urogenital defect is not in the above list!
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Old 12-09-2011
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its a uw question i was solvg...

i cant get y anal atresia is asso wit vacterl defect which are mesodermal anomalies?
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Old 12-09-2011
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urogenital is in list!!!....renal atresia...is 1 of tem others are fistulas mentioned abov , hypo n epispadias
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The list says kidney anomalies, not urogential atresia. Two differnt anatomical site, my dear
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google it or c uw q id 320
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I solved it in this way that if there is no anus means it may b some cloacal abnormality and failure of partition and recanalition and cloaca and urgenital septum are also involved in this process of partition n anal formation for reference u can c diagrams in keith l moore embryology
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If u c the diagram of urgenital septum and cloaca u will get the clue to this question hope it works for u !
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