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Old 12-23-2011
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Default P50 and O2 Hb dissociation curve

I just cant find why increase in P50 lead to curve diccociation to the right??
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Old 12-23-2011
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1. What is P50?

  • P50 is the partial pressure at which arterial O2 saturation is at 50%

2. What are the axis for the oxygen-haemoglobin dissociation curve?

  • The y-axis is the saturation
  • The x-axis is the partial pressure of O2

3. What does an increased P50 mean?

  • It means that a greater partial pressure of O2 is required to maintain a saturation of 50%
  • Take the normal O2-Hb dissociation curve and draw a horizontal line at 50% saturation. If the partial pressure corresponding to this saturation is increased does that mean a left or right shift of the curve?
  • Right-shift!
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The above post was thanked by:
Hamada (08-16-2014), riya10 (12-23-2011), sibb (12-24-2011), VVDieiev (07-11-2014)


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