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Old 12-26-2011
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Kidney Low sodium diet to calcium renal stones

How does a high sodium level increase calcium release from bone and exacerbate hypercaliuria (causing increased calcium renal stones)? I cant seem to understand the mechanism behind this....Uworld says that you have to give a low sodium diet in calcium renal stones....
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Old 05-08-2012
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In another UW Q they say that a low Na diet causes less water absorption in the GI and therefore decrease ECV and activation of RAAS which increases the GFR dt increase in AT II.
Since by default there is always 70 % of filtered Na and water reabsorbed in the PCT , the Na reabsorption in PCT will increase as a result of decrease dietary Na.
This increase in Na reabsorption is accompanied by increase Ca reabsorption as well via paracellular routs. Decreasing urinary calcium.

The concept of low dietary Na and RAAS activation is frequently tested on the USMLE
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The above post was thanked by:
DocSikorski (05-08-2012), ibrar (05-31-2015), shaan.medico (05-27-2013)


Physiology-, Renal-

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