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Old 12-31-2011
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Question Why Estrogen stimulates Prolactin release

why estrogen (ocp, pregnency) lead to stimulate prolactin production???
just like dopamine antagonist , just cant understand that??
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Old 12-31-2011
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Estrogen acts like a woman with contrasting effects . I am confused too
Can anyone list all the physiological effects of it, with explanation or example, plz?
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Old 12-31-2011
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Correct Answer

Estrogen inhibits prolactin inhibiting factor (Dopamine) -----> removal of the strain on prolactin production -----> increase prolactin
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Old 01-01-2012
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i just know after delivery estrogen and progest secretion decreases which allow prolactin to induce lactation.

this question is beyond the scope of step 1

just my opinion
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Old 01-01-2012
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Quote:
Originally Posted by step_enhancer View Post
i just know after delivery estrogen and progest secretion decreases which allow prolactin to induce lactation.

this question is beyond the scope of step 1

just my opinion
During pregnancy, estrogen enhance prolactin production ( by inhibiting dopamine) BUT at the same time estrogen prevent the upregulation of prolactin receptors in the breast so that NO MILK PRODUCTION during pregnancy ( because this will be an extra burden on the pregnant woman also if milk produced during pregnancy, whose gonna drink it ).. Anyway, after delivery of placenta ( which is the major source of estrogen production during pregnancy ) estrogen levels drop significantly allowing the already high level prolactin to start working immediately because the factor ( estrogen in this case) that was preventing its action on its receptors was removed ..
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Old 01-01-2012
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Quote:
Originally Posted by tiger73jo View Post
During pregnancy, estrogen enhance prolactin production ( by inhibiting dopamine) BUT at the same time estrogen prevent the upregulation of prolactin receptors in the breast so that NO MILK PRODUCTION during pregnancy ( because this will be an extra burden on the pregnant woman also if milk produced during pregnancy, whose gonna drink it ).. Anyway, after delivery of placenta ( which is the major source of estrogen production during pregnancy ) estrogen levels drop significantly allowing the already high level prolactin to start working immediately because the factor ( estrogen in this case) that was preventing its action on its receptors was removed ..
Thanks a lot i will make a note of this .in case it shows up in my exam

Last edited by step_enhancer; 01-01-2012 at 08:36 AM.
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Old 01-01-2012
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Quote:
Originally Posted by tiger73jo View Post
During pregnancy, estrogen enhance prolactin production ( by inhibiting dopamine) BUT at the same time estrogen prevent the upregulation of prolactin receptors in the breast so that NO MILK PRODUCTION during pregnancy ( because this will be an extra burden on the pregnant woman also if milk produced during pregnancy, whose gonna drink it ).. Anyway, after delivery of placenta ( which is the major source of estrogen production during pregnancy ) estrogen levels drop significantly allowing the already high level prolactin to start working immediately because the factor ( estrogen in this case) that was preventing its action on its receptors was removed ..

thanks alot that is so helpful
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