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Old 01-03-2012
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Question Some confusion about Potassium and Bicarbonate in DKA

Since in DKA we have acidosis why there is decrease in HCO3 bicarbonate
and why there is hyperkalemia if there is osmotic diuresis?
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Old 01-03-2012
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usually when there is acidosis H+ goes into the cell and K+ comes out of the cell resulting in the hyperkalemia but intracellular hypokalemia.

H+/K+ pump is present on the surface of the cells.

pts with diabetic ketoacidosis have intracellular hypokalemia ,so they r given glucose,insulin and K+ to normalize their intracellular K+ to prevent arrhythmias.
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Old 01-03-2012
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In DKA there is gain of fixed acids (ketone bodies ) causes excess (H+) ,
and since there should be an equilibrium in the reaction (CO2) <--> (H+)+(HCO3-) then the reaction should shift to the left forming more CO2 (which result in hyperventilation ) and less HCO3

for the hyperkalemia part i totally agree with step enhancer.
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flowerlady (01-03-2012), indigo (01-03-2012)


Electrolytes-, Pathology-, Physiology-

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