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  #1  
Old 01-03-2012
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GIT Small Intestine Pathology in Cholera!

On August 17, 1988, a 42-year-old man was treated for profuse, watery diarrhea, vomiting, and dehydration at an emergency room in Rifle, Colorado. On August 15, he had eaten approximately 12 raw oysters from a new oyster-processing plant in Rifle. Approximately 36 hours after eating the oysters, he had sudden onset of symptoms and passed 20 stools during the day before seeking medical attention. Stool culture subsequently yielded toxigenic Vibrio cholerae 01, biotype eltor. The patient had no underlying illness, was not taking medications, and had not traveled outside the region during the month before onset.
The oysters had been harvested on August 8, 1988, in a bay off the coast of Louisiana. Approximately 1000 bushels (200,000 oysters) arrived by refrigerator truck at the plant in Rifle on August 11. The patient purchased three dozen of these oysters on August 15. During a 6-day period, eight other persons shared the oysters purchased by the patient. None became ill. Although one of seven tested had a vibriocidal antibody titer of 1:640, none had elevated antitoxic antibody titers, and none had V cholerae 01 isolated from stool. Physicians and local health departments were asked to notify the Colorado Department of Health about similar cases, but no cases were reported.
What would you expect a biopsy of this patient's small intestine to show?

A. Hyperemia
B. Pseudomembrane
C. Flask-shaped ulcers
D. Enterocyte necrosis
E. Focal hemorrhage
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  #2  
Old 01-03-2012
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Either A or D,
will go for D
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Old 01-03-2012
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I feel A is the answer!!
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Matched!!!
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Old 01-03-2012
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I will go with A
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Old 01-04-2012
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Quote:
Originally Posted by scopusmount View Post
On August 17, 1988, a 42-year-old man was treated for profuse, watery diarrhea, vomiting, and dehydration at an emergency room in Rifle, Colorado. On August 15, he had eaten approximately 12 raw oysters from a new oyster-processing plant in Rifle. Approximately 36 hours after eating the oysters, he had sudden onset of symptoms and passed 20 stools during the day before seeking medical attention. Stool culture subsequently yielded toxigenic Vibrio cholerae 01, biotype eltor. The patient had no underlying illness, was not taking medications, and had not traveled outside the region during the month before onset.
The oysters had been harvested on August 8, 1988, in a bay off the coast of Louisiana. Approximately 1000 bushels (200,000 oysters) arrived by refrigerator truck at the plant in Rifle on August 11. The patient purchased three dozen of these oysters on August 15. During a 6-day period, eight other persons shared the oysters purchased by the patient. None became ill. Although one of seven tested had a vibriocidal antibody titer of 1:640, none had elevated antitoxic antibody titers, and none had V cholerae 01 isolated from stool. Physicians and local health departments were asked to notify the Colorado Department of Health about similar cases, but no cases were reported.
What would you expect a biopsy of this patient's small intestine to show?

A. Hyperemia
B. Pseudomembrane
C. Flask-shaped ulcers
D. Enterocyte necrosis
E. Focal hemorrhage
Not sure. B. Psudomembrane - in C difficile. Might well be A. hyperemia.
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Old 01-04-2012
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maybe it's A.

by the way, where did you get this question from?? is it a recall from usmle step 1??
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Old 01-05-2012
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The answer is A.

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  #8  
Old 01-05-2012
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Quote:
Originally Posted by scopusmount View Post
The answer is A.

Can you please post an explanation, if it was given with the answer?

Sent from my Desire HD using Tapatalk
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