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  #1  
Old 01-06-2012
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Neuro Wernicke encephalopathy

What part of the brain is injured in the Wernicke encephalopathy?

And how is it different from alcoholic cerebellar degeneration?
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Old 01-06-2012
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Originally Posted by indigo View Post
What part of the brain is injured in the Wernicke encephalopathy?

And how is it different from alcoholic cerebellar degeneration?
Alcoholic damage to the cerebellum affects the anterior vermis only and presents with gait ataxia.

Wernicke encephalopathy can show lesions in a few areas but most common is #1 mammillary body, #2 dorsomedial nuclei of thalamas.. It may also damage the anterior group nuclei, hippocampus and vermis as well but the first two I would say are most important..

WE presents with eye problems (ocular palsies), confusion and gait ataxia acutely and may also progress to include Korsakoff Psychosis which consists of anterograde + retrograde amnesia, and confabulations (if you can't remember anything then you just make everything up ).. At this point it is known as Wernicke-Korsakoff Syndrome

I would say that is the difference..
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Old 01-06-2012
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And also there is damage to periaqueductal gray matter in wernicke's. Thats why ocular palsies occur.
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Old 08-11-2012
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Originally Posted by Dr_Swagg View Post
Alcoholic damage to the cerebellum affects the anterior vermis only and presents with gait ataxia.

Wernicke encephalopathy can show lesions in a few areas but most common is #1 mammillary body, #2 dorsomedial nuclei of thalamas.. It may also damage the anterior group nuclei, hippocampus and vermis as well but the first two I would say are most important..

WE presents with eye problems (ocular palsies), confusion and gait ataxia acutely and may also progress to include Korsakoff Psychosis which consists of anterograde + retrograde amnesia, and confabulations (if you can't remember anything then you just make everything up ).. At this point it is known as Wernicke-Korsakoff Syndrome

I would say that is the difference..


WE includes anterograde amnesia
Korsakoff includes anterograde and retrograde amnesia.
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WE includes anterograde amnesia
Korsakoff includes anterograde and retrograde amnesia.
No WE doesn't.. Well it's not written in Rapid Review Pathology or Kaplan..
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Originally Posted by Dr_Swagg View Post
No WE doesn't.. Well it's not written in Rapid Review Pathology or Kaplan..
I'll double check that. I had this note from UW.
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Quote:
Originally Posted by Dr_Swagg View Post
Alcoholic damage to the cerebellum affects the anterior vermis only and presents with gait ataxia.

Wernicke encephalopathy can show lesions in a few areas but most common is #1 mammillary body, #2 dorsomedial nuclei of thalamas.. It may also damage the anterior group nuclei, hippocampus and vermis as well but the first two I would say are most important..

WE presents with eye problems (ocular palsies), confusion and gait ataxia acutely and may also progress to include Korsakoff Psychosis which consists of anterograde + retrograde amnesia, and confabulations (if you can't remember anything then you just make everything up ).. At this point it is known as Wernicke-Korsakoff Syndrome

I would say that is the difference..
nicely explained
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Old 08-12-2012
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Quote:
Originally Posted by Dr_Swagg View Post
No WE doesn't.. Well it's not written in Rapid Review Pathology or Kaplan..

wikipedia:

Wernicke encephalopathy is a syndrome characterised by ataxia, ophthalmoplegia, nystagmus, confusion, and impairment of short term memory. It is caused by lesions in the medial thalamic nuclei, mammillary bodies, periaqueductal and periventricular brainstem nuclei, and superior cerebellar vermis.

Korsakoff's psychosis is characterized by:
  1. anterograde amnesia (inability to form new memories)
  2. retrograde amnesia (loss of existing memories)
  3. confabulation (false perceptions or memories)
  4. hallucinations[2]
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