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Old 01-16-2012
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Kidney membranous glomerulonephritis

Which of the following is not correct regarding the membranous glomerulonephritis?
A) Both light and electron microscopy show greatly thickened capillary walls and basement membrane.
B) The immune complexes are distributed in intramembranous and epimembranous (subepithelial) locations within and on the basement membrane.
C) The "spike and dome" appearance results from the extension of basement membrane between and around the immune deposits.
D) Granular deposits of IgG and C3 are apparent on immunofluorescence.
E) The disease is slowly progressive with good respond to steroid therapy.
F) Associations sometimes include hepatitis B, syphilis, malaria infection, gold salts, penicillamine, malignancy, and SLE.
G) The disorder sometimes causes renal vein thrombosis.
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Old 01-16-2012
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E?
Minimal change disease is the only one that responds well to steroid therapy.
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  #3  
Old 01-16-2012
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All options appear to be correct , found that membranous GN also responds to steroids well

http://www.ncbi.nlm.nih.gov/pubmed/7348534

but still as usmle wants us to know that MCD has rapid response to steroids thus E could be the answer .....
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Old 01-17-2012
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Quote:
Originally Posted by Hitman View Post
All options appear to be correct , found that membranous GN also responds to steroids well

http://www.ncbi.nlm.nih.gov/pubmed/7348534

but still as usmle wants us to know that MCD has rapid response to steroids thus E could be the answer .....
You're right, But for USMLE purposes --> E is correct.
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  #5  
Old 02-02-2012
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F these disease are associated with MPGN I guess
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Old 02-02-2012
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G


it is steroid responsive
and it is caused by gold penicillamine sle.. etc etc
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