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  #1  
Old 01-19-2012
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Default Portal Hypertension

A 45-year-old male alcoholic with a history of portal hypertension presents with vomiting of blood (hematemesis) and hypotension. He denies any history of vomiting nonblood material or retching prior to vomiting blood. During workup he dies suddenly. Which of the following histologic changes is most likely to be seen in a biopsy specimen taken from his esophagus?
A.
Metaplastic columnar epithelium

B.
Decreased ganglion cells in the myenteric plexus

C.
Dilated blood vessels in the submucosa

D.
Mucosal outpouchings

E.
Numerous intraepithelial neutrophils
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  #2  
Old 01-19-2012
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Idea!

Quote:
Originally Posted by scopusmount View Post
A 45-year-old male alcoholic with a history of portal hypertension presents with vomiting of blood (hematemesis) and hypotension. He denies any history of vomiting nonblood material or retching prior to vomiting blood. During workup he dies suddenly. Which of the following histologic changes is most likely to be seen in a biopsy specimen taken from his esophagus?
A.
Metaplastic columnar epithelium

B.
Decreased ganglion cells in the myenteric plexus

C.
Dilated blood vessels in the submucosa

D.
Mucosal outpouchings

E.
Numerous intraepithelial neutrophils
I'm thinking of C. The symptoms remind me of portal hypertension resulting from liver cirrhosis.
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  #3  
Old 01-19-2012
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Default

C dilated blood vessel in submucosa ( portal hypertension---eso. varices )
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  #4  
Old 01-19-2012
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Default

C

Either too easy a question or i just got tricked.
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