Relation between Pulse presssure and mean arterial pressure - USMLE Forums
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Old 07-26-2015
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Smile Relation between Pulse presssure and mean arterial pressure

Can anybody clear the relation in between PP and MAP? Like will they change directly or inversely or there is no such proportional thing?
Thanks in advance
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Old 07-26-2015
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Originally Posted by Helping_hands View Post
Can anybody clear the relation in between PP and MAP? Like will they change directly or inversely or there is no such proportional thing?
Thanks in advance
MAP=COxTPR

Pulse pressure is directly related with cardiac output. In other words, the more the pressure difference between systolic BP and diastolic BP the more volume was ejected. That is due to the fact that aorta has low compliance but that is a topic of another discussion.

Anyways, PP is directly related to CO and CO is directly related to MAP.
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Old 07-26-2015
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Smile So, if we increase CO it gonna increase PP hence MAP too

Quote:
Originally Posted by Nodo View Post
MAP=COxTPR

Pulse pressure is directly related with cardiac output. In other words, the more the pressure difference between systolic BP and diastolic BP the more volume was ejected. That is due to the fact that aorta has low compliance but that is a topic of another discussion.

Anyways, PP is directly related to CO and CO is directly related to MAP.
So if we increase CO we gonna increase PP and thus we can increase MAP. Is it possible to have increase MAP with decrease PP?
Thanks a lot
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Old 07-27-2015
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Originally Posted by Helping_hands View Post
So if we increase CO we gonna increase PP and thus we can increase MAP. Is it possible to have increase MAP with decrease PP?
Thanks a lot
Yes. I think it is incorrect to think about changes in the single physiologic parameters without considering the others but, theoretically, if TPR goes up (afterload goes up) stroke volume will go down and CO will also go down and PP is going to go down. But I can not imagine that happening in a real life situation since the body does everything it can to maintain CO.
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Old 07-27-2015
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Originally Posted by Helping_hands View Post
So if we increase CO we gonna increase PP and thus we can increase MAP. Is it possible to have increase MAP with decrease PP?
Thanks a lot
This is wrong. Increase in CO doesn't equal increase in PP. You can increase CO by either increasing SV or by increasing HR. If you increase HR, CO and therefore MAP increase, but PP doesn't change.
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