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Old 01-22-2012
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Syringe Developing a live attenuated vaccine!

A biotech company is developing a vaccine against an emerging pathogen. Which of the following pathogens is most likely to require a live attenuated vaccine?

A. DNA virus
B. Enveloped virus
C. Helical virus
D. Icosahedral virus
E. Naked virus
F. RNA virus
G. Syncytial virus
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Ans . B enveloped virus .........
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Old 01-22-2012
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Embarrassed I'd go with A

hi, thanks for the question a rather tough one....

i'll try it and go with A) DNA virus because it's the only kind of virus i can't think of a killed vaccine...(maybe a bit of a naive way to think but maybe it works...)

B) enveloped: killed vaccine: Rabies, Influenza; attenuated: Rubella, Measles, small pox etc.

C) helical: Killed: Rabies, Influenza; attenuated: Mumps etc.

D) icosahedral: killed: HAV, Polio; attenuated: Rubella, Polio;

E) naked: killed: HAV, Polio; attenuated: Polio;

F) RNA: killed Influenza; attenuated: Mumps

G) syncytial virus: attenuated or killed in general not possible

what do you think????
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Old 01-22-2012
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A or B are not the correct answer
(i had guessed B myself, but was wrong).
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where is the Qs from ?? Looks like F is the ans .......
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Old 01-22-2012
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The question is from a Kaplan Self-Assessment exam i took today.

the answer is G.
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Quote:
Originally Posted by khushi.chahal View Post
The question is from a Kaplan Self-Assessment exam i took today.

the answer is G.
thanx
could you give an explanation or the QID? my pharmacology book says that there are no attenuated or killed vaccines for syn vir....
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Old 01-23-2012
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Quote:
Originally Posted by MedPharm View Post
thanx
could you give an explanation or the QID? my pharmacology book says that there are no attenuated or killed vaccines for syn vir....
Kaplan's explanation to this question was something along the lines of: syncitial viruses are viruses that cause cell to cell fusion, therefore they are rarely extracellular, so therefore we need something that will go into the cells and kill the virus.
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