Bilateral Ovarian Tumors - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 01-29-2012
Hope2Pass's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 1,684
Threads: 213
Thanked 1,600 Times in 660 Posts
Reputation: 1610
Question Bilateral Ovarian Tumors

Bilateral ovarian masses are identified on pelvic examination of a 40-year-old woman. Ultrasound examination reveals multiloculated cystic masses involving both ovaries. The patient is treated with total abdominal hysterectomy with removal of both adnexa. Pathologic examination demonstrates papillary carcinoma producing serous fluid. Which of the following tumor markers would be most useful in monitoring for recurrence?


(A) Alpha-fetoprotein
(B) Bombesin
(C) CA-125
(D) PSA
(E) S-100
Reply With Quote Quick reply to this message
The above post was thanked by:
bunny (01-29-2012)



  #2  
Old 01-29-2012
Hitman's Avatar
USMLE Forums Master
 
Steps History: Not yet
Posts: 928
Threads: 17
Thanked 539 Times in 375 Posts
Reputation: 549
Default

Ans ......... C........
Reply With Quote Quick reply to this message
  #3  
Old 01-29-2012
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 646
Threads: 52
Thanked 762 Times in 256 Posts
Reputation: 773
Default

AFP---yolk sac tumor

Bombesin -- small cell lung cancer/ neuroblastoma/gastric cancer

CA125-- ovarian cancer

PSA- prostate

s-100: APUD cell cancers
Reply With Quote Quick reply to this message
The above post was thanked by:
Moloch (01-29-2012)
 
  #4  
Old 01-29-2012
USMLE Forums Scout
 
Steps History: Not yet
Posts: 28
Threads: 1
Thanked 10 Times in 8 Posts
Reputation: 20
Default

Correct me if I am wrong, but isn't CA125 raised in every abdominal tumors?
Reply With Quote Quick reply to this message
  #5  
Old 01-30-2012
USMLE Forums Newbie
 
Steps History: Not yet
Posts: 2
Threads: 0
Thanked 2 Times in 1 Post
Reputation: 12
Default

Ca-125 is raised only in tumors originating from ovaries, helps in differentiating from metastatic tumors to the ovaries, from other locations
Reply With Quote Quick reply to this message
  #6  
Old 01-30-2012
DocSikorski's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 1,353
Threads: 94
Thanked 877 Times in 507 Posts
Reputation: 890
Default

Quote:
Originally Posted by Moloch View Post
Correct me if I am wrong, but isn't CA125 raised in every abdominal tumors?
that's CEA
__________________
Ambition is a dream with a V8 engine. EP
Reply With Quote Quick reply to this message
The above post was thanked by:
Moloch (01-31-2012)
  #7  
Old 01-30-2012
USMLE Forums Addict
 
Steps History: 1+CK+CS
Posts: 109
Threads: 2
Thanked 41 Times in 34 Posts
Reputation: 51
Default

pg223 of FA 2010

CA-125 = Ovarian, Malignant epithelial tumors

CEA = usually colorectal and pancreatic (GI)
Reply With Quote Quick reply to this message
The above post was thanked by:
Moloch (01-31-2012)
  #8  
Old 01-31-2012
Hope2Pass's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 1,684
Threads: 213
Thanked 1,600 Times in 660 Posts
Reputation: 1610
Default

The correct answer is C. The tumors are serous papillary cystadenocarcinomas of the ovaries. These tumors express CA-125 and are apparently derived from the surface epithelium of the ovaries.

Alpha-fetoprotein (choice A) is not produced by this type of ovarian tumor but can be produced by testicular tumors and, less commonly, by ovarian tumors with a yolk sac tumor component.

Bombesin (choice B) is a marker for neuroblastoma, small cell carcinoma, gastric carcinoma, and pancreatic carcinoma.

PSA (choice D) is a marker for prostatic carcinoma.

S-100 (choice E) is a marker for melanoma, neural tumors, and astrocytomas.
Reply With Quote Quick reply to this message



Reply

Tags
Pathology-, Reproductive-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
malignant tumors of stomach? Evergreen USMLE Step 1 Forum 23 01-03-2012 04:18 AM
Parotic gland tumors Q2? Evergreen USMLE Step 1 Forum 9 11-07-2011 08:36 PM
brain tumors Amenah USMLE Step 1 Forum 4 09-30-2011 02:04 PM
Bilateral carpal tunnel convalescence USMLE Step 2 CK Forum 1 09-04-2010 11:21 PM
bilateral pneumonitis khushboo USMLE Step 1 Forum 4 05-25-2010 03:16 AM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)