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Old 02-06-2012
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Blood anemia and oxygen content

can someone please explain this:

anemia : Po2 normal, % saturation normal, and o2 content decreased
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Old 02-06-2012
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Pa02 is the partial pressure of oxygen, is the dissolved oxygen in the blood,
O2sat, is the 02 that binds to Hb...

If you have a normal sat, and a normal Pa02, but a total 02 diminished that means that you probably have anemia...


O2 content: (1.34 x Hb) x Sat02 x (Pa02x0.003)

that means, those 3 factors are included in the total 02 content, and because sat and pa02 are normal, that means the Hb is down, probably chronic anemia.

Other examples are Methemoglobin, where Sa02 is down, because the heme iron is oxidized to +3 preventing 02 binding.
Carbon monoxide poisoning, where CO has more affinity to Hb than 02, so the Hb is saturated, but not by 02.

If you still don't understand, please read the first chapter of Goljan, it's clear as water there.
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