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  #1  
Old 02-07-2012
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Default Immortal cell line

A scientist successfully generates an immortal cell line of neuronal origin using tissue removed from a human brain cancer. The cells were incubated at body temperature in a solution containing the usual electrolytes found in cerebrospinal fluid. When the cells are analyzed, which ion is expected to have the lowest intracellular concentration?

A.BicarbonateB.CalciumC.ChlorideD.PotassiumE.Sodium
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Quote:
Originally Posted by scopusmount View Post
A scientist successfully generates an immortal cell line of neuronal origin using tissue removed from a human brain cancer. The cells were incubated at body temperature in a solution containing the usual electrolytes found in cerebrospinal fluid. When the cells are analyzed, which ion is expected to have the lowest intracellular concentration?
(b) calcium:because cell is in rest
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Old 02-07-2012
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ans .......E ...... sodium has the lowest conc intracellularly ....
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3. Composition of Body Fluid Compartments

Ion ECF (mmol/L) ICF (mmol/L)
Na+ `` 143 = 9

K+ `` 5 = 135

Ca2+ `` 1.3 = <0,8

Mg2+ `` 0.9 = 25

Cl- `` 103 = 9

HCO3- `` 24 = 9

Last edited by riya rai; 02-07-2012 at 08:22 AM.
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Old 02-07-2012
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CSF has a bit weird ion concentrations that slightly differ from plasma.

I remember that pH is lower, and I think both Na/K are lower in the CSF, but within the cell...

Something tells me its A) bicarb...
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A comparison of the composition of CSF and plasma reveals that:
1. CSF proteins are -1 % that of plasma;
2. CSF calcium levels are -50% that of plasma;
3. CSF glucose levels are -60% that of plasma;
4. CSF chloride and magnesium levels are higher than plasma;
5. CO2 diffuses rapidly, and HCO3 slowly, from the plasma into the CSF.

so,i`ll go for choice a,bicarb.
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ill go with calcium.....!!!!!!!!
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Quote:
Originally Posted by docord View Post
A comparison of the composition of CSF and plasma reveals that:
1. CSF proteins are -1 % that of plasma;
2. CSF calcium levels are -50% that of plasma;
3. CSF glucose levels are -60% that of plasma;
4. CSF chloride and magnesium levels are higher than plasma;
5. CO2 diffuses rapidly, and HCO3 slowly, from the plasma into the CSF.

so,i`ll go for choice a,bicarb.
u got the stem wrong......it says compare intracellular with the extracellular environ........not CSF n plasma levels!!!!
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My guess is Na
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Old 02-08-2012
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Quote:
Originally Posted by anomali View Post
u got the stem wrong......it says compare intracellular with the extracellular environ........not CSF n plasma levels!!!!
didnt got the stem wrong,but i guess since bicarb is low in csf,it may be also lower inside those cells. not too much sure though.so,what brought you to ca?
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Quote:
Originally Posted by riya rai View Post
3. Composition of Body Fluid Compartments

Ion ECF (mmol/L) ICF (mmol/L)
Na+ `` 143 = 9

K+ `` 5 = 135

Ca2+ `` 1.3 = <0,8

Mg2+ `` 0.9 = 25

Cl- `` 103 = 9

HCO3- `` 24 = 9

i go with this......!!!!!!! not sure thou, lets wait for the correct one
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the answer is calcium
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Quote:
Originally Posted by scopusmount View Post
the answer is calcium
can you explain it.
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  #14  
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it sounds the whole csf story is a trick.we should forget about the csf and simply answer this question"which one has the lowest ic concentration?" which is ca.
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