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Old 02-12-2012
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Question Changes in muscle histology after 3 months of weight-lifting.

A 16-year old boy participates in a study of exercise and muscle hypertrophy. After a pretraining biopsy specimen of the quadriceps muscle is obtained, he begins a weight-lifting program to increase the mass and strength of the quadriceps muscle. After 3 months of training, a second biopsy is taken. Compared with the pretraining sample, the post-training sample is most likely to show which of the following findings?

Number of Mitochondria / Amount of Actin per Myocyte / Total # of myocytes
A. increase / increase / increase
B. increase / increase / no change
C. increase / no change / increase
D. increase / no change / no change
E. no change / increase / increase
F. no change / increase / no change
G. no change / no change / increase
H. no change / no change / no change
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Old 02-12-2012
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number of mitochondria--- increase

number of actin filaments--- increase

number of muscle cells--- REMAIN THE SAME
(hypertrophy vs hyperplasia)
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Old 02-12-2012
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yes.....it would be B)
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Old 02-12-2012
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to "B" or not to "B", that is the question... I choose to "be"...
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Old 02-12-2012
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Its B...........
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Matched!!!
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Old 02-13-2012
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Is it D......?
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D
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Old 02-13-2012
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Nbme 11 question.
Answer is b
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Old 02-13-2012
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yes its B ........
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Old 02-13-2012
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can anyone explain about the no. of actin increasing
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Old 02-13-2012
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Quote:
Originally Posted by jinni View Post
can anyone explain about the no. of actin increasing
Satellite Cells
Satellite cells function to facilitate growth, maintenance and repair of damaged skeletal (not cardiac) muscle tissue (2). These cells are termed satellite cells because they are located on the outer surface of the muscle fiber, in between the sarcolemma and basal lamina (uppermost layer of the basement membrane) of the muscle fiber. Satellite cells have one nucleus, with constitutes most of the cell volume.
Usually these cells are dormant, but they become activated when the muscle fiber receives any form of trauma, damage or injury, such as from resistance training overload. The satellite cells then proliferate or multiply, and the daughter cells are drawn to the damaged muscle site. They then fuse to the existing muscle fiber, donating their nuclei to the fiber, which helps to regenerate the muscle fiber. It is important to emphasize the point that this process is not creating more skeletal muscle fibers (in humans), but increasing the size and number of contractile proteins (actin and myosin) . This satellite cell activation and proliferation period lasts up to 48 hours after the trauma or shock from the resistance training session stimulus (2).

The amount of satellite cells present within in a muscle depends on the type of muscle. Type I or slow-twitch oxidative fibers, tend to have a five to six times greater satellite cell content than Type II (fast-twitch fibers), due to an increased blood and capillary supply (2). This may be due to the fact that Type 1 muscle fibers are used with greatest frequency, and thus, more satellite cells may be required for ongoing minor injuries too........
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Old 07-09-2015
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In the question, It says amount of actin per myosin, so it would be unchanged? ok actin and myosin both increase but actin per myosin is same isnt it?
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Old 07-09-2015
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Quote:
Originally Posted by bcelikten View Post
In the question, It says amount of actin per myosin, so it would be unchanged? ok actin and myosin both increase but actin per myosin is same isnt it?
it in per myocyte...ie a muscle cell
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Old 01-01-2016
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Quote:
Originally Posted by Hitman View Post
yes its B ........
He's doing some dynamic weight training not static endurance.
Muscles have a mix of both type 1 and type 2 fibres, the latter develops in response to fast high intensity exercises.

So shouldn't type 2 fibres be the one which develop?

If the case
1. Mito same (type 2 fibres = white = less mito)
2. Actin increased
3. Total myocytes same

I think the answer should be F
Can someone clarify?
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