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Old 04-04-2010
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Default immunoglobulin genes

Which of the following genes involved in the synthesis of immunoglobulins are linked on a single chromosome?

A. C gene for gamma chain and C gene for alpha chain
B. C gene for gamma chain and C gene for kappa chain
C. V gene for kappa chain and C gene for the epsilon chain
D. V gene for lambda chain and C gene for kappa chain
E. V gene for lambda chain and V gene for heavy chain
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Old 04-06-2010
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A - C gene for gamma and C gene for alpha
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Old 04-07-2010
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arrgghh this is a crazy questino. i read it but i had no idea we were supposed to indulge on it truely. i dont even have my notes on me at this moment.

sigh....
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Old 04-07-2010
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Idea!

lolz dr. seetal no need to worry dude i shall xplain u


The correct answer is A. The genes for the synthesis of the entire heavy chain are present on human chromosome 14. Of the options given above, the only genes that are present on one chromosome are for the
C (constant) regions of the heavy chains. Remember, the heavy chains determine the identity of the immunoglobulin isotypes: IgG, IgM, IgA, IgD, and IgE.

Choice B: The C gene for the gamma heavy chain is on chromosome 14 and the C gene for the kappa light chain gene is on chromosome 2.

Choice C: The V gene for the kappa light chain gene is on chromosome 2. The C gene for the epsilon heavy chain is on chromosome 14.

Choice D: The V gene for the lambda light chain gene is on chromosome 22. The C gene for the kappa light chain gene is on chromosome 2.

Choice E: The V gene for the lambda light chain gene is on chromosome 22 and the V gene for the heavey chain gene is on chromosome 14.
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Old 04-07-2010
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Quote:
Originally Posted by doctorF View Post
lolz dr. seetal no need to worry dude i shall xplain u


The correct answer is A. The genes for the synthesis of the entire heavy chain are present on human chromosome 14. Of the options given above, the only genes that are present on one chromosome are for the
C (constant) regions of the heavy chains. Remember, the heavy chains determine the identity of the immunoglobulin isotypes: IgG, IgM, IgA, IgD, and IgE.

Choice B: The C gene for the gamma heavy chain is on chromosome 14 and the C gene for the kappa light chain gene is on chromosome 2.

Choice C: The V gene for the kappa light chain gene is on chromosome 2. The C gene for the epsilon heavy chain is on chromosome 14.

Choice D: The V gene for the lambda light chain gene is on chromosome 22. The C gene for the kappa light chain gene is on chromosome 2.

Choice E: The V gene for the lambda light chain gene is on chromosome 22 and the V gene for the heavey chain gene is on chromosome 14.
ok i just looked at the notes. thank u. yes i remember now.
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