Potassium Iodide to Treat Hyperthyroidism? - USMLE Forums
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Old 02-17-2012
shafaliMD's Avatar
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Thyroid Potassium Iodide to Treat Hyperthyroidism?

apparently no one likes to answer my post... but i will keep posting and keep on being determined.

if potassium iodide is used to treat hyperthyroidism and its mechanism of action is to inhibit the release of T3 and T4... wouldn't that make the thyroid gland enlarge and possibly even cause a goiter?
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Old 02-17-2012
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LOL!

Well, it's not that I don't want to answer it, it's just that I'm toooo laaaazzzyy to look for the answers... I'm not sure if it's even a trick question or a clarification.

But since your first line made me laugh, here goes:

YES, it can induce hyperthyroidism. "In susceptible individuals, iodides can induce hyperthyroidism (jodbasedow phenomenon) or precipitate hypothyroidism". "Disadvantages of iodide therapy include an increase in intraglandular stores." -- Both are quoted directly from Katzung's Basic and Clinical Pharmacology 10th ed p. 627.

Well, I'll dwell into the details but I'm sleepy... I'll just post again if you need to go in-depth or if no one else will explain it. LOL!

Last edited by d_wiqed; 02-17-2012 at 04:07 PM.
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Old 02-17-2012
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thanks.... i guess i gotta get hostile to get an answer lol
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