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Old 02-17-2012
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Urine Sample Sickle Cell Anemia and Hematuria!

I have read Sickle cell anemia doesn't manifest Hematuria....any reasons ? please explain briefly
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Old 02-18-2012
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Hi, doctordexter!

I was pleasantly surprised to know that sickle cell doesn't manifest with hematuria. I tried researching about it and I came across this in the internet:

This is from medscape/emedicine work-up of sickle cell anemia (http://emedicine.medscape.com/articl...up#aw2aab6b5b5).
"Patients with sickle cell anemia often have hematuria and isosthenuria."

I wonder if maybe there are exceptions to the rule or special cases wherein sickle cell doesn't manifest hematuria? Or maybe I misunderstood your question? I'll gladly look more in-depth into it when I have time.
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Old 02-18-2012
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Oh,so Sickle cell does show hematuria thenI might have got the wrong information regarding it.
Goljan says hematuria is seen in Sickle cell disease due to microinfarctions.
and he added we need to always order Sickle screen in black pts with unexplained hematuria.
@d_wiqed thanks for the correction.As for step 1 i think no need to look for the exceptions...
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Old 02-18-2012
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Quote:
Originally Posted by doctordexter View Post
Oh,so Sickle cell does show hematuria thenI might have got the wrong information regarding it.
Goljan says hematuria is seen in Sickle cell disease due to microinfarctions.
and he added we need to always order Sickle screen in black pts with unexplained hematuria.
@d_wiqed thanks for the correction.As for step 1 i think no need to look for the exceptions...
what I am sure of is that sickle cell trait have heamaturia
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