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Old 10-19-2015
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Default Organellar proteins

Where are the organellar proteins synthesized?
RER or free ribosomes?
In FA its given as free ribosomes but un Uworld it says RER
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Quote:
Originally Posted by datson View Post
Where are the organellar proteins synthesized?
RER or free ribosomes?
In FA its given as free ribosomes but un Uworld it says RER
RER synthesizes proteins to be exported,
free ribosomes synthesize cellular proteins.
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All proteins (mRNA) start translating on free ribosomes. The following three types are then shifted to ER for completion of translation,

1. Protiens that are to be secreted (eg insulin)
2. Protiens that are to be stored in lysosomes
3. Protiens that form parts of cell membrane

the rest complete their translation on free ribosomes.
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Thanks. I guess that covers the high-yield topics.

What about enzymes in peroxisomes, SER and microsomes?
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I would call free ribosomes for that job.
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