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Old 02-26-2012
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Default Ig A NEPHROPATHY

just wanted to make sure of this that henoch scholein purpura can make IgA deposition in kidney so is that the same as berger disease , is there a difference between them or it is the same and just called berger in kidney???
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Old 02-26-2012
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Quote:
Originally Posted by rose View Post
just wanted to make sure of this that henoch scholein purpura can make IgA deposition in kidney so is that the same as berger disease , is there a difference between them or it is the same and just called berger in kidney???
its associated but it does not mean that when you have IgA nephropathy you will have HSP..
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Old 02-26-2012
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Henoch-Schonlein purpura can, like IgA nephropathy (aka Bergers disease), also be caused due to the increase in IgA, usually following an upper respiratory infection.
So this IgA can deposit in the kidneys and cause Bergers disease, or in the vessels and cause HSP.
So I'd imagine its not uncommon to see both Henoch-Schonlein purpura and Bergers disease at the same time, because both are a result of increased IgA.
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Old 02-26-2012
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yeah..more or less same
Ig A(after uri) when produced in excess and deposited in
1)kidney:forms immune complex deposition causing IG a nephropathy
2)deposted in vessels(leukoclastocytic infiltration) causes vasculitis
3)when deposited in joints causes arthritis and
4) when in abdomen causes discomfort and pain
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