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  #1  
Old 03-04-2012
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Default Biochemistry question please help

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Some cells can produce no net ATP. These cells expend some free energy in a reaction catalyzed by phosphoglycerate mutase rather than producing ATP with that energy. Which of the following cells are most likely to utilize the pathway described above?

a) hepatocytes
b) erythrocytes
c) skeletal muscle cells
d) adipocyes
e) neurons
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Old 03-04-2012
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Originally Posted by usmle_taker View Post
Question
Some cells can produce no net ATP. These cells expend some free energy in a reaction catalyzed by phosphoglycerate mutase rather than producing ATP with that energy. Which of the following cells are most likely to utilize the pathway described above?

a) hepatocytes
b) erythrocytes
c) skeletal muscle cells
d) adipocyes
e) neurons
B. Erythrocytes, no mithochondria.
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Old 03-04-2012
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B. Erythrocytes

phosphoglycerate mutase, if im not mistaken, turns 1-3-bisphosphoglycerate into 2,3-BPG. and we're all familiar with 2,3-BPG and its role on RBCs.
Also, RBCs have no mitochondria and therefore produce no net ATP from such a pathway.
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Old 03-04-2012
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thank you!!! @LatinGeorge, Dr.NickRiviera
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Old 03-04-2012
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B erythrocytes
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Old 03-05-2012
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Erythrocytes
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Old 03-06-2012
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Quote:
Originally Posted by usmle_taker View Post
Question
Some cells can produce no net ATP. These cells expend some free energy in a reaction catalyzed by phosphoglycerate mutase rather than producing ATP with that energy. Which of the following cells are most likely to utilize the pathway described above?

a) hepatocytes
b) erythrocytes
c) skeletal muscle cells
d) adipocyes
e) neurons
are you sure it wasnt Bisphosphoglycerate mutase?
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Old 03-06-2012
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Its erythrocytes..utilize biphospgoglycerate mutase to generate ATP.c the glycloysis pathway.its been mentioned there.
erythrocytes have this enzyme to produxe 2,3bpg in glycolysis...which peoduces rightward ahift of the curve to unload o2so that more can be loaded in the lungs.k
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Old 03-06-2012
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Default mistake

Generate NO net ATP
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