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Old 04-13-2010
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Idea! Virulence Factor?

A 66-year-old man is undergoing chemotherapy for leukemia has a 3-dau history of progressive fever, headache, nausea, and deterioration of mental activity. Analysis os CSF shows lymphocytic pleocytosis, a normal glucose concentration, and a slightly increased protein concentration. The causal agent is presumptively identified bu a positive India ink test and later confirmed with culture. Which of the following is a major virulence factor of the infecting organism producing this disease?

A) Antigenic variation
B) Exotoxin
C) Immunoglobulin protease
D) Leukicidin
E) Polysaccharide capsule
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Old 04-13-2010
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Question E

polysaccharide capsule?
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Old 04-13-2010
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E.That s cryptococcus neoformans
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Old 04-14-2010
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yeah c.neoformans. i dont waste time thinking when i come across India Ink.. but is it only the capsule that is virulent? this also seems to be a famous question innit? ive come across the India Ink c.neoformans quite a few times. symptoms can be diff, but the India Ink is always mentioned. do u think its possible to ask the question of c.neoformans without India Ink as a clue?
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Old 04-14-2010
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yep cryptococcus with the capsule!!!
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