NBME 11 block 2 - USMLE Forums
 USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
 Home USMLE Articles USMLE News USMLE Polls USMLE Books USMLE Apps
 USMLE Forums NBME 11 block 2
 Register FAQs Members List Search Today's Posts Mark Forums Read

 USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam

#1
03-08-2012
 USMLE Forums Veteran Steps History: Not yet Posts: 270 Threads: 34 Thanked 221 Times in 119 Posts Reputation: 231
NBME 11 block 2

Q4:
I picked A, but key says B...what do you think??

Q20:
This is wierd. At low dose drug Y acts like a competitive antag. and at high dose it acts like a non-competitive antag. So whats the answer...competitive or non-competitive???

Q23:
I pick D

Q31:
I pick C....key is wrong.

Q50:
I don't get it....explain

#2
03-08-2012
 USMLE Forums Master Steps History: 1+CK+CS+3 Posts: 1,353 Threads: 94 Thanked 873 Times in 506 Posts Reputation: 886

could you provide full question stems please?

I did this one online, I would like to discuss this one.

(you are not allowed to copy-paste, but retyping the q is just fine)

Thank you!
__________________
Ambition is a dream with a V8 engine. EP
#3
03-08-2012
 USMLE Forums Master Steps History: 1+CK+CS+3 Posts: 1,353 Threads: 94 Thanked 873 Times in 506 Posts Reputation: 886

Block2.q4:

I think the answer is B.

The significant difference is 4% (small magnitude as the stem explains)
==============
If it was A, p value should have been > 0.05.

p<0.05 = 5% chance that there is no difference between groups, null hypothesis is rejected.
========
C - p value was small enough to justify, but they didn't so it doesnt make sence...
========
D - samples were high enough to achieve statistical significance, no sence also.
__________________
Ambition is a dream with a V8 engine. EP
 The above post was thanked by: haga (03-08-2012)
#4
03-08-2012
 USMLE Forums Master Steps History: 1+CK+CS+3 Posts: 1,353 Threads: 94 Thanked 873 Times in 506 Posts Reputation: 886

Block2.q23:

1800 x 7 = 12,600 - her weekly caloric intake.

she needs to lose 7,000 calories per week to lose 2lb per week (3500 x 2)

12,600 - 7000 = 5,600 should be her weekly intake

5,600/7 = 800

so - decrease calories by 500 and start walking 1hr per day (also 500)

Choice D
__________________
Ambition is a dream with a V8 engine. EP
#5
03-08-2012
 USMLE Forums Master Steps History: 1+CK+CS+3 Posts: 1,353 Threads: 94 Thanked 873 Times in 506 Posts Reputation: 886

Block2.q31

It's C, its pretty straight forward.

q50

I am pretty sure it is B.

CGG increase and methylation dicrease the transcription activity in fragile X syndrome.

=====

In q20 I think I picked noncompetitive antagonist and it wasn't wrong.
But I have no clue about that one.
__________________
Ambition is a dream with a V8 engine. EP
#6
03-08-2012
 USMLE Forums Master Steps History: 1+CK+CS+3 Posts: 1,353 Threads: 94 Thanked 873 Times in 506 Posts Reputation: 886

I am not sure about the answer for the following questions in the first block:

12
13
19
23
33
42

and in the Block # 2:

3
7
8
31
49
50
__________________
Ambition is a dream with a V8 engine. EP
#7
03-08-2012
 USMLE Forums Veteran Steps History: Not yet Posts: 270 Threads: 34 Thanked 221 Times in 119 Posts Reputation: 231

Quote:
 Originally Posted by DocSikorski In q20 I think I picked noncompetitive antagonist and it wasn't wrong.But I have no clue about that one.
I also guessed noncompetitive. I think I know whats going on now.

When it's given in a low dose its acting like a proper noncompetitive, pushes curve to the right and decreases potency as there are still some receptors available for Drug X to act.

But when you give it in a very high dose, it saturates ALL the receptors. None are available for Drug X to work, so along with right shift and decreased potency we will also see decreased efficacy, cause Drug X cannot work at all.
 The above post was thanked by: DocSikorski (03-08-2012)
#8
03-08-2012
 USMLE Forums Master Steps History: Not yet Posts: 928 Threads: 17 Thanked 538 Times in 375 Posts Reputation: 548

Hey hope you guys get the notes i sent you ...... they are pretty good ...
 The above post was thanked by: DocSikorski (03-08-2012), haga (03-08-2012)

 Tags NBME-

Message:
Options

## Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
User Name:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
 AMG IMG ---
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

 Not yet Step 1 Only CK Only CS Only 1 + CK 1 + CS 1+CK+CS CK+CS 1+CK+CS+3 ---
Favorite USMLE Books
 What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
 Where you live. Leave blank if you don't want to tell.

## Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.