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Old 03-08-2012
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Drug Beta blockers and lipid metabolism

What effect do Beta-blockers have on lipid metabolism?
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Old 03-08-2012
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Here's a factoid

It causes Type IV hyperlipoproteinemia - increased VLDL
TG & Ch > 300 (Ch - 250-500)
Other agents causing Type IV
alcholosim, OCP, DM CKD, Thaizides
Familial hypertriglyceridemia

Sx- eruptive xanthomas, increased risk for CAD, PVD

I hope others can chip in and explain the pathogenesis please.

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Old 03-09-2012
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all i know, and i think all you need to know, is that B-blockers increase LDL levels.

Also, nonselective ones will decrease gluconeogenesis so are contraindicated in diabetics as they prolong the time of glucose recovery in starvation or attacks of hypoglycemia.
"inflammable means flammable!? What a country."
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Biochemistry-, Pharmacology-

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