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Old 04-15-2010
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Question Abnormal Circadian Variation

A 45-year-old man has abnormal circadian variation in body temperature, disruption of the sleep-wake cycle, and an impaired nocturnal surge of secretion of melatonin. An MRI of the brain is most likely to show a lesion involving which of the following nuclei?

(A) Accessory optic
(B) Lateral preoptic
(C) Pretectal
(D) Suprachiasmatic
(E) Supraoptic
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Old 04-15-2010
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Wink Answer is D

The suprachiasmatic nucleus or nuclei is a tiny region on the brain's midline, situated directly above the optic chiasm. It is responsible for controlling circadian rhythms. The neuronal and hormonal activities it generates regulate many different body functions in a 24-hour cycle.

The pretectum, also known as the pretectal area, is a region of neurons found between the thalamus and midbrain. It receives binocular sensory input from the retinae, and is the region responsible for maintaining the pupillary light reflex.
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Old 04-15-2010
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I always wanted to know. If a tumor arises at that area or lets say a mass effect to that area wouldnt cause sleeping problems? Or defective sleep cycel?
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Old 04-16-2010
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the answer is indeed D.. and marco about the tumor (good question), if someone would care to explain.
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Old 04-16-2010
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Arrow It's explained above

Quote:
Originally Posted by Seetal View Post
the answer is indeed D.. and marco about the tumor (good question), if someone would care to explain.
It seems that you are so in hurry posting and so you don't really read the replies. I already explained the matter above. I was even thanked for it!
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Old 04-16-2010
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Quote:
Originally Posted by laithbv View Post
It seems that you are so in hurry posting and so you don't really read the replies. I already explained the matter above. I was even thanked for it!
err... thanks for yr reply. but it turns out u were in such a hurry to reply. I meant if someone could answer dr. marco's reply. why so cranky?

PS: when I post a question I look for explanations that members give because I cant find them. So I READ the replies and save them in my PC.
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Old 04-16-2010
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No answer for the tumor question I think there is a big concept here that i just cant figure out
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Old 04-16-2010
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Default Yes, of course

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Originally Posted by marco View Post
No answer for the tumor question I think there is a big concept here that i just cant figure out
What concept are you missing! Of course any tumor putting pressure on the hypothalamus will disturb the circadian rhythm
have a look at this example
http://www.springerlink.com/content/qum3254834600u83/
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