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Old 03-11-2012
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Drug How to treat akathisia?

Is the dose of neuroleptics increased or decreased in order to treat akathisia (arising as a result of dopamine blockade)?
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Old 03-11-2012
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Akathisia — Akathisia is the most common form of EPS and present as side effect of anti-psychotics. It usually presents as motor restlessness with a compelling urge to move and an inability to sit still. Individuals with milder akathisia may describe a subjective feeling of restlessness but not show restless motor behavior.

Treatment options for akathisia include:
  • A cautious antipsychotic dose reduction, if feasible, should be attempted first, with close monitoring of the patient for exacerbation of psychotic symptoms.
  • If decreasing the antipsychotic drug dose is unfeasible or inadequate, then you treat with a benzodiazepine.
  • If treatment with a benzodiazepine is not effective, a beta blocker such as propranolol can be used.
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