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Old 03-17-2012
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Drug Antacid causing diarrhea

A 54-yr-old woman comes because of a 2 week history of severe heart burn and regurgitation of gastric contents at bedtime. Use of an OTC antacid decreased her symptoms but caused moderately severe diarrhea in the morning. Which of the following ingredients in the antacid is the cause of diarrhea?
a) aluminum hydroxide
b) calcium carbondate
c) magnesium trisilicate
d) simethicone
e) sodium bicarbonate

Please also explain why
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Old 03-17-2012
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I believe this is Magnesium. I don't exactly have a reason behind it but I know First Aid mentions that Mg = must go to the bathroom as in diarrhea.

And Aluminum hydroxide causes constipation so u know that can't be it.

Calcium carb causes hypercalcemia, rebound acid increase, and it can chelate causing decrease effectiveness of other drugs.

Hope this somewhat helps!
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Old 03-17-2012
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Magnesium , dont know why exactly , but as the previous post , Mg causes diarrhea
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Old 03-18-2012
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Default magnesium is a laxatives

- ans. c) magnesium trisilicate

- I know that magnesium is a laxatives..hence, it can cause diarrhea....ever heard of laxative magnesium citrate? it's used saline laxativeand to completely empty the bowel prior to a major surgery or colonoscopy.

- Individuals with chronic malabsorptive problems such as Crohn's disease, gluten sensitive enteropathy, regional enteritis, and intestinal surgery may lose magnesium through diarrhea and fat malabsorption
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